The
Pharmacology Scrolls
Pharmacology of
Autacoids
What are autacoids?
Fast acting messengers
Autacoids work locally, appearing out of nowhere, casting their effects, and vanishing just as quickly!
🔮 The Autacoid Guilds:
📜 Histamine – The prankster of the bunch! Found in mast cells, it loves causing itching, allergies, and acid secretion(Beware: Histamine’s sneeze spells are strong!). Antihistamines act as its magical counterspells.
🔥 Serotonin (5-HT) – The multitasking wizard! It controls mood, gut motility, and platelet aggregation. Too much? Serotonin Syndrome! Too little? Depression!
💨 Bradykinin – The stormcaller of inflammation! It dilates blood vessels, increases pain, and brings swelling like a cursed spell.
⚡ Eicosanoids (Prostaglandins, Leukotrienes, & Thromboxanes) – The elemental forces of inflammation, clotting, and pain. Think of them as the fire, wind, and water of immune responses!
💡 Final Wizardry Notes:
Autacoids don’t travel far; they act locally and rapidly, like whispered incantations. But beware—when overactivated, they can lead to allergic reactions, pain, or chronic inflammation! Lucky for us, drugs like antihistamines, NSAIDs, and steroids exist to neutralize their chaos! 🧙♂️✨
